![]() ![]() That means that a 200 MB files usually takes an hour to download, a 1GB file takes 5 hours. Top speed I’ve ever attained with a download was around 1.5Mbps. This is a first time that this has happened to me, but it seems to be one of the major complaints about dropbox. I checked the folder and there was nothing. A few days later he emails me to ask when he could expect the transcripts back. The automatic sync does not always work! Recently a client uploaded some video into our shared dropbox folder.With the desktop app, the limit is determined by the free space in your account. In addition the maximum file size you can upload using the web interface is 300MB. Having said that, there are various ways you can increase your limit while using a free account to around 16GB. Most other cloud storage services offer at least 5GB. Your maximum storage space for your account is a measly 2GB.With so many uses, and the simplicity of access, what’s the downside to using dropbox? While writing this dropbox review, three things straight away jump to mind. That’s it! After creating an account, you will need to verify the email address in order to activate the account. To reiterate, all you need to create a dropbox account is a valid email address that you have access to. You will require a valid email address and your account is always linked to that email address. To start using dropbox, you need to create an account. Hell, you can run a website from dropbox! Dropbox also has a two step verification system that you can use for sensitive data, for instance in academic research. You can backup files into your drop box account, including your WordPress blog. You can, with dropbox, sync files between two devices a mobile phone and your laptop, for instance. This allows you to share large files via email. Dropbox creates a link to each file that you can share with anyone. Dropbox has a myriad of features which makes it usage limitless. It’s a great place to store your CV, photos, music and videos!īut that’s not all. This means if you have an internet connection, you can always access it anywhere, anytime. Dropbox allows you to store and share any type of digital file in cloud. As a cloud based service, dropbox is basically data storage space hosted on Amazon Simple Storage Service (S3). The keywords here are secured and drop off. What is dropox? The dictionary definition of a drop box is a secured receptacle or container where you can drop off or store stuff. I’ve yet to test the simultanious editing of documents in dropbox -so I can comment if it has improved. I’ll never need to delete anything from my dropbox account- unless I want to. I am sure with more bandwidth I would get higher speeds.Īnd in the last few months Dropbox has set the maximum storage for pro accounts at 1TB! That’s a lot of space. i sometimes get download speed of about 7 Mbps, which is impressive considering I have a 7.2 Mbps connection. I have to say that dropbox speeds have improved in the past year. Paid $100/per and so far not much to complain. Update: Finally found a need to upgrade my dropbox account to Pro. However, I’ve only used their free service and never found the need to upgrade to a paid service (quite pricey $10 a month!). I’ve used the service extensively, over the last two years, to share files with my transcription clients. ![]() It’s about time I did.Ĭaveat: I don’t work for dropbox and I’m not getting paid to write this review. I’ve already compared dropbox and the newest kid in block, in cloud sharing, wetransfer. I’ve already blogged on how you can share multiple files easily using dropbox. This dropbox review takes a closer look at the services that dropbox cloud storage service has to offer and suggests 3 must use tips on how to efficiently use dropbox. ![]()
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Razer's ultra-portable gaming laptop is $800 off for Black FridayRazer's Blade 14 light, powerful laptop is down to its lowest price ever on Amazon thanks to an early Black Friday deal.Ī New 'Atomic Clock' Transforms Deep Space ExplorationNASA reduced the size of the atomic clock to that of a toaster oven and activated it in space to compare with the experiment results on Earth. well now DARPA’s ROCKn program aims to make optical atomic clocks portable. Radiant could provide safe, portable nuclear energy within the next 5 yearsFormer SpaceX engineer and Radiant CEO Doug Bernauer told us 'execution is everything.' LIVE: Crews battling 60-acre brush fire threatening structures in East San Jose, CAL FIRE sayĬrews are battling a 60-acre brush fire that is threatening structures in East San Jose, according to CAL FIRE. Portable atomic clocks Typically, optical atomic clocks are large cumbersome machines, but DARPA's ROCKn program aims to make them smaller and lighter so they can be fitted into military vehicles, and even satellites. The program addresses the emerging DOD need to: Decrease reliance on GPS Increase system accuracy Reduce co-lateral damage Increase effective range Reduce SWAP&C Micro-PNT Objective Parameters Units SOA SOA MEMS micro-PNT Size 3mm 1.6x107 6.5x104 8 Weight 2gm 34. Optical atomic clocks are so accurate, in fact, that they wouldn't have lost a second over the universe's entire existence of more than 13 billion years. The most accurate type of atomic clock is the optical atomic clock, which replaces the microwaves with a beam of light, boosting the accuracy by a factor of 100. The technology uses a beam of microwaves to measure the frequency of atoms as they change energy state. See Also Atomic clocks could provide a solution by allowing field units to tell the time with ultra-precise accuracy, without the need to connect to GPS. To this end, the modern military is heavily reliant on GPS, but the technology isn't always available and it can even be jammed by adversaries. Even an error of a billionth of a second could cause a missile to miss its target. In military operations, nanosecond-level accuracy is required for military craft to fire weapons at high speed and at extreme ranges. is hosting a Proposers Day in support of an anticipated Broad Agency Announcement (BAA) for the Atomic Clock with Enhanced Stability (ACES) program. ![]() DARPA announced the ROCkN program which aims to build a super-accurate optical atomic clock compact enough to fit inside a military aircraft. Proposers Day for Atomic Clocks with Enhanced Stability (ACES) Program (Archived). ![]() ![]() ![]() Our product offerings include millions of PowerPoint templates, diagrams, animated 3D characters and more. is brought to you by CrystalGraphics, the award-winning developer and market-leading publisher of rich-media enhancement products for presentations. get out of the room and always stayed with Manni in front of the window. Schafer and developed and published by LucasArts for Microsoft Windows. Then you can share it with your target audience as well as ’s millions of monthly visitors. Grim Fandango Remastered > General Discussions > Topic Details.0 Pages 20 Ppi. Kids say ( 1 ): Grim Fandango Remastered is proof that a great game is timeless. I run Windows 10 Pro 圆4 - could this be the cause of D3D11 games not. We’ll convert it to an HTML5 slideshow that includes all the media types you’ve already added: audio, video, music, pictures, animations and transition effects. 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Try to use game booster you can get some greatĤ) Random Crashes Getting random crashes while 1) Right click My Computer (or navigate to Device Manager directly) 2) Open Device Manager 3) Select audio- ,video- and game devices 4) Choose high definition audio 5) Go to drivers tab 6) Click update drivers 7) Choose option 'find driver from this computer' 8) Choose option 'select from list of. JustĬlick on I to access inventory and choose item Your game freezes stop using mouse to select the Nothing works rather than pressing backspace toĮnter into the original mode. GrimFandango.exe, Propiedades, Compatibilidad, selecciona Ejecutar este programa en modo compatibilidad para Windows 8. C:Program Files (x86)SteamsteamappscommonGrim Fandango Remastered. The situation becomes worse when you fail to save Hola, me pasaba exactamente lo mismo (windows 10, en un surface). Resolve this press ESC during the game and hitģ) Low FPS and Freezes Game abruptly freezes Game but still getting French Solutions To Steam language in English and redownloaded the Translation but when I started this game I find
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You’ll want to know how to put the tones on your smartphone. ![]() ![]() ![]() This was annoying when you were trying to go for some weird easter egg or a star puzzle. If I had a problem with it, it was that too often the puzzles required you to restart the levels, which reset everything in the world. I don't know if I agree with Cordeos, while some of the puzzles had specific solutions, there were many where you could kind of fumble around and get it. Those floating islands you mentioned, Merus, were also affecting to me. That being said, there were some really wonderful moments that pulled me into some of the emotional ideas behind the game. It kept me engaged, and the writing was clever in places, but it felt a lot of the time like the writers were REALLY HITTING YOU OVER THE HEAD WITH THE CONCEPTS. I also didn't understand what the non-linear design added to the game, the in between spaces felt like clutter to me. I find this level of finickyness really annoying. I got the feeling that there was one, precise way to solve the puzzles and if you are a little off in timing or placement of objects you lose. I know what you mean, there was something about the puzzles I found really off putting. I just clearly wasn't in the mood for it when I played it, and now I have no desire to go back to it. ![]() All the pieces are there to make a very good game. I don't think it's a bad game by any possible stretch. ![]() As I get older, I have less and less time to game, which means I have less and less patience for open-world games. I preferred the linearity of Portal to this more open design. I didn't want to keep playing out of the hopes that it would get better in case it didn't, and I would have wasted two hours instead of one. The game didn't do anything to capture my attention in the first hour of it, and that's sort of my threshold. I didn't like the environment, the authority figure, the computer system, or the puzzle mechanics. ![]() It didn't vary enough from Portal to capture my interest. I think I'm the opposite of folks in this thread. I don't know if this was intentional, that the most depresing audio logs were paired with areas where that's the only thing you can think about, but it worked. It is an experience to have your brain fired up, ready to put two and two together, and be deprived of material other than contemplating oblivion, as you carefully try and solve puzzles in order to disturb the. The music is funereal, and the atmosphere is eerie. The game runs on hypothesis forming and testing, but not these tetromino puzzles, and alongside the puzzles is a very conspicuous collectible that plays an audio message from one of the game's characters, towards the end of her life, and it's clear from context that she doesn't have long to live, and nothing she has done will have any meaning unless some post-human intelligence manages to find it and comprehend it. There's a castle in the distance, or perhaps a tomb, and to open it you have to solve five tetromino puzzles, at least one of which is quite complex. There's a part in the game where you are on a beautiful, peaceful floating island. I appreciate that unlike most puzzle games, the very hardest puzzles are challenges not to execute with more pieces, but to break existing puzzles to send them into a state that shouldn't be possible. Also disliked the final puzzles to unlock the doors/floors, I'm really not that great at solving those, I just gave up at a certain point and looked at the solution in a walkthrough, in my opinion it wasn't needed to have this kind of puzzle when your game mechanic already is to solve puzzles. I finished it in about 21-22 hours, by the end I was already tired. However, I think the game could be way shorter. But it was pretty good, it's definitely great to see games talking about those subjects. The game kinda left me depressed a little bit, existentialist stuff can do that to me. What got me into the game though was it's story, it always felt so mysterious and writing is fantastic, I felt so connected with the Alexandra character, her visions about the main subject of the game sounded pretty honest and smart, I share some of the fears and insecurity that she has. The puzzles were smart and only some of them were a but frustrating for me, I guess I'm not really that good with "puzzlers", had to look for walkthrough on some of later levels. I finished the game last week and it was pretty amazing, one of the best of 2014 really - probably my favorite PC title of the year. To be honest, I didn't have any problem with the levels, never got lost or couldn't find where to go. The levels have signs which indicate the pieces in it, and they are marked/crossed when you get the pieces, so you can see if you already got all the sigils. ![]() ![]() ![]() Add Gangland to your Watchlist to find out when it's coming back For World of Warcraft on the PC, a GameFAQs message board topic titled Ever see Gangland on the History channel Breed MC DVD - Gangland Season 5 by the History Channel. How thousands of gangs in all over 50 states and around the world and over 150 countries changed and reshaped our history It usually aired on Thursday evenings although it has been known to arbitrarily change days every so often. The History Channel's Secret to Success: No History □CLICK HERE FOR WIN NEW IPHONE 14 - PROMOCODE: NFHR52□ TV tends to sway people very easily, especially the uneducated.History Channel Gangland nocamermoi1975 JanuHistory Channel Gangland I am sure that made some people think STL is a bad place to go. He referenced those bogus numbers based on 350K people. He referenced a chart that shows Osaka has some minimal number of murders compared to New York and St. Tony was making a point about how low the crime rate is in Osaka Japan, which is where he was that episode. I remember seeing an episode of 'Anthony Bourdain's No Reservations. Louis because they read that bogus list stating that STL is the murder capital of the U.S. These are the same people that wouldn't come to St. I am sure Little Rock is like every other city, overall nice, has it's rough areas. I think these shows have a negative overall effect on some people's views of the a city because they are not educated enough to realize this is a nationwide issue. I think it did have a negative effect on that city and people's perceptions at that time. Everyone I know had seen it and was talking about it. It was pretty good and I remember people saying it opened their eyes that this kind of violence wasn't just a problem for big cities. ^HBO aired a documentary focused on gang life in Little Rock, AR of all places in the mid 90's. Louis was bad you should have checked out the episode on New Orleans or Detroit. Chicago has been covered multiple times but it's not gonna change my opinion that it's a great city. I watch it every week, I still think it's a good show the only thing about it is you have to have sense enough to realize that the cities they are covering aren't giant cesspools of drugs and violence for the most part. I mean pretty much, that's their job to sensationalize everything. They painted the entire city as a war zone, and then focused on a few square miles of it. I don't expect it to say that in our city it's "every man for himself." Maybe if they said "Along MLK drive between _ & _, it's every man for himself." But they didn't. It's a show about the reality of thugs and murderers. Shimmy wrote:What do you guys expect, a 47 minute commercial about our great neighborhoods? I've seen this show many times and every episode is depicted in such a way. But to make it sound like the whole city is a "Gangland" is horribly one-sided. Louis suffers from one of the nation's worst crime problems (along with some of its worst schools, widespread unemployment and underemployment, worsening transit, high poverty, etc.). Louis was one big free-for-all where anyone could and does get murdered. Multiple times they quoted people who said that St. Maybe I misunderstood the context of the show, but I never heard them stop once to say that this was strictly the reality of gang members. Not a lot of real estate to duck and dodge unless you go out to St. Louis is more dense than other big cities it's only 66.2 square miles. They went to the same elementary, middle school often times high school if they made it that far. (Walnut Park East) not to know about the gang members on Garesche Ave. It's impossible for the gang members from Emerson Ave. There are gangs in Walnut Park East and West that are separated by Riverview Blvd. But if you have any plans on being a major player than you will be found out. You can't really be making moves in the drug trade and not have anyone not find you out unless you are small potatoes. ![]() ![]() All the players in the game know each other. Louis I can tell you what they said is pretty much true. We are strictly talking about criminals here and in that small sector of the population.which the majority is located in the North and West side of the city, and as a resident of North St. And all gang members are famous in this tiny, provincial place, where "every man is for himself". Louis is a small town (almost rural), where everyone knows everyone else. ![]() ![]() ![]() Immersive audio formats (Dolby Atmos Music and Sony 360 Reality Audio) Master audio quality (2,304 - 9,216 kbps) Minimal access to video content consisting of performances, documentaries, and interviews.Īvailable to college and High School students 16 years or olderĪvailable to all active and retired US Military personnelĪvailable to all active and retired EMS, EMT, Firefighters, and Police Officers Here’s a breakdown of those plans and what they come with: Each plan comes with four subscription types priced at discounted rates. Tidal offers two types of paid plans – Premium and HiFi. Tidal Plans and Pricing Tidal subscription plans. And with new management onboard (Square, Inc.), we can expect to see big changes in the future. As such, it’s possible that Tidal’s actual subscriber count is still within the 1-5 million range as of 2021.ĭespite this, Tidal remains one of the top choices for audiophile-level sound quality. It also didn’t help that Tidal posted a $55.3 million loss in 2019, likely testament to a dwindling subscriber base. At the time, the claim was met with much contention, particularly after the release of Kanye’s The Life of Pablo, wherein the album’s total streaming numbers didn’t add up to the total number of subscribers on the platform. ![]() The last time Tidal released official subscriber numbers was in 2016, when they supposedly hit 3 million paid subscriptions. ![]() But is it really worth the 20-dollar monthly investment? Let’s take a deeper look and find out! Today, Tidal is certainly one of the more expensive streaming apps, largely due to unique exclusive content and ultra hi-res audio. acquired a majority ownership stake with the goal of “finding new ways for artists to support their work.” By September 2015, Tidal reported having as many as 1 million subscribers, a number heavily contested later on. Tidal eventually launched in five more European territories – Belgium, Ireland, Finland, the Netherlands, and Luxembourg. In January 2015, Project Panther Bidco Ltd., a holdings company owned by rapper Jay-Z, stepped in and acquired the service for $54 million. The service first launched in the UK, US, and Canada in 2014. Tidal is a music and video streaming service initially owned by Aspiro, a Norwegian-Swedish tech company. We delve into Tidal’s strengths and weaknesses to see if this premium music streaming service is worth its hefty subscription price. ![]() ![]() ![]() Or better yet, allow designating part of the trackpad as click-only-area. But I decided that was too much work especially as I'm pretty confident Apple just will have to swallow their pride and provide gesture disabling in the near future. Being a veteran programmer I toyed with the idea of re-writing, reverse engineering, disassembling and hacking the trackpad driver. At least it makes using NeoOffice bearable.īut still the user experience leaves something to be desired.Īnd yet this would be so easy to solve with a little bit of programming. With this it is possible to assign the annoying gestures to harmless keys which partially solves the issue. In the end I found Will Henderson's MultiClutch control panel that allows you to re-assign the gestures to key board shortcuts. I even considered buying the Good Old Trackpad as a spare part and fitting it to the new MacBook, after all I do machining work on my spare time and the trackpad is a more or less standard USB device, so it might have worked out of the box software-wise. In my desperation I considered returning the MacBook Pro to the shop but that would have left me with my old MacBook whose backlight is so dim I need flashlight to see the text, dead battery and mere 2 GB RAM backed by a measly 80 GB disk. But no real solution.Īnd it should be relatively simple to just disable the gesture in software. So I started googling high and low with phrases like "apple multi-touch trackpad sucks" and indeed I found many people who were as annoyed as I was. ![]() I know the people in Redmond think they know "the right and only way" their software can and should be used, but "Et tu Brute"? Ever heard of user empowerment? What? No way to disable them? Come-on Apple, what were you thinking. My documents kept zooming in and out like the end of days were fast approaching.Īt this point I decided something had to be done.Ĭonfidently I went into the to the System Preferences with the intent to turn the gestures off. The shit really hit the fan when I started to use NeoOffice which actually obeys those gestures, unlike so many other applications that just silently ignore them. In practice it fails too often, turning an accidental non voluntary twitch of your thumb into a gesture, most often resulting zoom in/out action. The Apple engineers, to their credit, have realized this and have written the device driver to distinguish a resting thumb from a multi finger gesture, so you can do rest your thumb there. Except that the new multi-touch trackpad has no button. Most users, when they are using the trackpad, use the index finger to move the mouse cursor around and rest their thumb on the trackpad button, ready to click when needed. Granted, it takes a little bit more force than you want to exert with a lever as long as your index finger, but on the other hand you really want to use the side of your thumb to click anyway. Not just tap, but good old-fashioned proper resounding click. So you will disable the tap-to-click, and I guess the Apple engineers have realized this and equipped the trackpad with proper tactile feedback click feature that allows you to click by actually pressing the trackpad anywhere. If you do touch typing on a laptop, sooner or later your hands will accidentally touch the trackpad and the cursor will jump to some random place on the screen. It just generates too many accidental clicks. The tap-to-click feature does not really work. ![]() Zoom in/out and rotate are kind of cool, but I do not need them that often at all, I could easily live without them. After using it you wonder how you can live without it. I hate it.ĭon't get me wrong, I love some of the gestures on the trackpad, like the two finger scroll, which is totally addictive and performs flawlessly. I love it.Įxcept the new multi-touch trackpad. I even do graphics, CAD drawing and PCB layout using the trackpad. I never use a mouse, a trackpad has the best ergonomics for a touch typist. I'm a heavy user of computers, I do programming for living typing all day long. Have been using it for more than ten years on three Macs and several PC laptops. I'm a veteran touchpad / trackpad user and lover. Or if you want, you can just skip my rant and fast forward to the bottom of the page to see the solution. How can Apple make such a blunder.īefore you get all flamed up and tell how clever and cool it is, let me explain myself. ![]() There, I've said, I feel so much better now.Ī few months ago I got a brand new MacBook Pro with the new buttonless Multi-Touch trackpad (see picture on the left) and ever since I've been trying to get used to it. The New MacBook Pro Multitouch Trackpad Sucks About Spare Time Labs Spare Time Labs 2.0 ![]() ![]() ![]() Google-cloud-bigquery 3.4.2 requires grpcio=1.47.0, but you have grpcio 1.34.1 which is incompatible.Ĭupy-cuda11x 11.0.0 requires numpy=1.20, but you have numpy 1.19.5 which is incompatible.Ĭmdstanpy 1.1.0 requires numpy>=1.21, but you have numpy 1.19.5 which is incompatible.īokeh 2.4.3 requires typing-extensions>=3.10.0, but you have typing-extensions 3.7.4.3 which is incompatible.Īstropy 5.2.1 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible.Īrviz 0.15.1 requires numpy>=1.20.0, but you have numpy 1.19.5 which is incompatible.Īrviz 0.15.1 requires typing-extensions>=4.1.0, but you have typing-extensions 3.7.4.3 which is incompatible. Grpcio-status 1.48.2 requires grpcio>=1.48.2, but you have grpcio 1.34.1 which is incompatible. Jax 0.4.6 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible. Jaxlib 0.4.6+cuda11.cudnn86 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible. Librosa 0.10.0.post1 requires typing-extensions>=4.1.1, but you have typing-extensions 3.7.4.3 which is incompatible. Matplotlib 3.7.1 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible. Pydantic 1.10.6 requires typing-extensions>=4.2.0, but you have typing-extensions 3.7.4.3 which is incompatible. Xarray-einstats 0.5.1 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible. Xarray 2022.12.0 requires numpy>=1.20, but you have numpy 1.19.5 which is incompatible. This behaviour is the source of the following dependency conflicts. Raise ValueError('No training data provided.')ĮRROR: pip's dependency resolver does not currently take into account all the packages that are installed. SampleGeneratorFace(training_data_src_path, random_ct_samples_path=random_ct_samples_path, debug=self.is_debug(), batch_size=self.get_batch_size(),įile "/content/ NON/samplelib/SampleGeneratorFace.py", line 48, in _init_ Model = models.import_model(model_class_name)(įile "/content/ NON/models/ModelBase.py", line 193, in _init_įile "/content/NON/models/Model_SAEHD/Model.py", line 676, in on_initialize Initializing models: 100% 5/5 įile "/content/ NON/mainscripts/Trainer.py", line 46, in trainerThread Press enter in 2 seconds to override model settings. Silent start: choosed device NVIDIA A100-SXM4-40GB Silent start: choosed model "Pretrain320" Thank you Mr Narcissistrader13 for providing a fix.īut it seems the fix has ended, at least for SAEHD training. ![]() If you decided to give a unique name to deepfacelab fork say dfl2 then in Collab you have to replace deepfacelab with dfl2 Note: It's wise to not share your GitHub fork and try to give a unique name else Google will add that repo to its ban list as well. Now create a new code and paste this (paste in a single cell or multiple) Remove the entire "Install or update DeepFaceLab" cellī. Now edit the collab file that we use from repo like thisĪ. Then edit requirements-colab.txt in your forked repo to thisĬolab will install instantly compatible with Python 3.9 and it doesn't have to build from scratch (that's why it takes more time to install deepfacelab) Google disconnects your session after 5 minutes since DFL is in their ban list Old code is based on Python 3.6 and it requires 3.9Ģ. ![]() ![]() ![]() Both anaphylactic and anaphylactoid reactions are similar in their appearance and treatment, and consequently the terms are often used interchangeably ( 12). Anaphylactoid reactions resemble anaphylaxis but are independent of IgE and, although compounds have been identified that act directly on cell membranes of mast cells, the exact mechanism for these reactions remains unclear ( 12). Anaphylaxis, a Type I (immediate) hypersensitivity mediated by IgE, is the most serious complication in dogs. Reactions to insect envenomation fall into 5 main categories: local pain and swelling, larger regional reaction, anaphylactic reaction, serum sickness (delayed-type hypersensitivity) occurring 3 d to 2 wk after envenomation, and a rare delayed toxic reaction in humans seen within 24 h after severe envenomation characterized by hemolysis, coagulopathy, hepatopathy, thrombocytopenia, and disseminated intravascular coagulation (DIC) ( 1, 11). Hyaluronidase causes breakdown of connective tissue and promotes further uptake and spread of venom ( 6). Peptide 401 causes mast cells to release histamine and vasoactive amines causing vasodilation ( 1). ![]() Melittin has also been associated with acute myocardial ischemia, producing arrhythmias ( 6, 10). This in turn releases myoglobin and hemoglobin, which have been linked to acute tubular necrosis and acute kidney injury (AKI) in humans and other species, including dogs ( 7– 9). Melittin, acting synergistically with phospholipase A 2, disrupts cell membranes of certain mammals and causes lysis of erythrocytes, leukocytes, platelets, myocytes, and vascular endothelium ( 6). The main components of bee venom are: melittin, peptide 401 (mast cell degranulating peptide), phospholipase A 2, hyaluronidase, histamine, dopamine, acid phosphatase, apamine, and norepinephrine ( 5), with melittin being the main component of venom both by amount and lethality. The venom sac continues to contract outside the bee’s body and 100% of the venom is delivered within 60 s ( 4). Honeybees are only able to sting once, as their barbed stinger catches in the victim’s skin, pulling the stinging apparatus from the bee’s body causing the bee to die. The venom in the sting can cause pathology ranging from local benign lesions to severe life-threatening systemic reactions. Although honeybees are comparably more docile than most of these venomous hymenopterans, they are very protective of their hives and they will attack humans or animals that pose a threat to their habitat. The 3 groups of Hymenoptera most frequently responsible for physical symptoms relating to allergic reactions seen in veterinary hospitals are: Apidae (bees), Vespidae (hornets, wasps, and yellow jackets), and Formicidae (fire ants) ( 3). Severe systemic allergic reactions in dogs living in North America most commonly occur because of an insect bite or sting, and the most clinically important encounters originate from insects belonging to the order Hymenoptera ( 1, 2). ![]() |
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